Seven of the most frequent spinocerebellar ataxias (SCAs) are caused by a pathological expansion of a cytosine, adenine and guanine (CAG) trinucleotide repeat located in exonic regions of unrelated genes, which in turn leads to the synthesis of polyglutamine (polyQ) proteins.PolyQ proteins are prone to aggregate and form intracellular inclusions, w
Study on load imbalance system of hoist based on frequency conversion control
For the load imbalance system of hoist based on frequency conversion control, Siemens PLC is adopted as the core of the elevator control system and the closed-loop vector control mode of Emerson CT SPM series inverter is adopted to realize wide range, high precision speed regulation and stable starting and stopping.It has the functions of Fake Lash
Market Impacts of a Transmission Investment: Evidence from the ERCOT Competitive Renewable Energy Zones Project
Texas has experienced a rapid Pulsar development of wind power over the last 20 years.Since wind power was developed mostly in desolate areas that are remote from urban centers due to its nature conditions, Texas implemented the Competitive Renewable Energy Zones (CREZ) project, the goal of which is to integrate the wind supply regions with the lar
The pluripotency transcription factor Nanog represses glutathione reductase gene expression in mouse embryonic stem cells
Abstract Objective Redox homeostasis maintenance is essential to bring about cellular functions.Particularly, embryonic stem cells (ESCs) have high fidelity mechanisms for DNA repair, high activity of different antioxidant enzymes and low levels of oxidative stress.Although the expression and activity of antioxidant enzymes are reduced throughout t